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Soho Aneco Develops Water-Soluble HPR Vitamin A/Retinol Derivative Using Co-Solvency Technology

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Courtesy of Envato

Soho Aneco Chemicals Co., Ltd. has recently introduced a groundbreaking innovation in the skincare industry with the development of a water-soluble hydroxypinacolone retinoate (HPR) using co-solvency technology. Known as AC-HPR-W2 SACOS, this new ingredient was launched at the in-cosmetics Asia event in November 2024. The company’s new development follows its earlier releases of AC-HPR, a high-purity powder, and AC-HPR-S10, a 10% oil-soluble version of HPR, which has gained significant attention in the anti-aging market.

Soho Aneco Develops Water-Soluble HPR Vitamin A/Retinol Derivative Using Co-Solvency Technology

HPR (INCI: Hydroxypinacolone Retinoate) is a derivative of retinoic acid and pinacol, formulated to be milder and more stable than other forms of vitamin A. The new AC-HPR-W2 SACOS, a 2% water-soluble version of HPR, aims to solve the challenges of integrating HPR into aqueous systems. This is achieved using a co-solvency method that combines two or more solvents to improve the solubility of ingredients that are typically insoluble. By optimizing the solvent mixture, the solubility and bioavailability of HPR are enhanced, making it more effective and suitable for diverse formulations.

Soho Aneco Develops Water-Soluble HPR Vitamin A/Retinol Derivative Using Co-Solvency Technology

The advancement of AC-HPR-W2 SACOS is seen as a significant step forward in the skincare industry, particularly in anti-aging formulations. Soho Aneco’s HPR has been gaining market share for its powerful anti-aging properties and is expected to increasingly replace the more commonly used forms of vitamin A. The ingredient’s stability and bioavailability make it a preferred choice in modern skincare formulations.

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In addition to its superior solubility, HPR has shown promising results in clinical testing. It has been proven to be non-irritating and is highly effective due to its high purity and low molecular weight, allowing for better absorption into the skin. The ingredient is praised for its enhanced activity, making it an ideal addition to anti-aging products.

Soho Aneco’s commitment to innovation in the vitamin A derivative space continues to push the boundaries of skincare science, and its HPR technology is poised to revolutionize the industry with its enhanced stability, solubility, and skin benefits.

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