During the poster session, taking place from October 15-17 at Iguazu Falls, the company will highlight the connection between skin circadian rhythm and GN, an upcycled personal care ingredient that functions as a glycosylated citrus polyphenol.
Naringin, the aglycone of GN, is recognized for its beneficial physiological properties, including anti-inflammatory and antioxidant effects. However, its extremely low solubility has previously limited its application in personal care products.
By combining glucose and Naringin using Nagase Viita’s proprietary enzyme technology, the water solubility of GN increased by over 6,000 times compared to that of regular naringin. This enhancement is crucial, as GN is scientifically proven to improve skin elasticity, making it an asset for anti-aging formulations.
To further investigate GN’s effects on skin health, Nagase Viita explored its relationship with circadian rhythm, the body’s internal biological clock. Recent advancements in dermatological science have shown that circadian rhythms influence not just sleep patterns but also regulate essential physiological functions, including skin barrier repair and water retention.
It’s also understood that disruptions in skin circadian rhythm, often caused by lifestyle changes and daily stressors, can lead to skin dryness and roughness. These findings have prompted personal care companies to develop skincare products specifically designed for morning and night use: daytime products aim to reduce stress and external disturbances, while nighttime products focus on nourishing and repairing the skin during sleep.
In this study, Nagase Viita examined how GN impacts the expression of clock genes and related genes, uncovering its ability to mitigate circadian rhythm disturbances induced by oxidative stress in epidermal keratinocytes. Nagase Viita to present circadian rhythm research in Brazil, underscoring the ingredient’s potential in skin health enhancement.
